actym therapeutics word
actym therapeutics logo

Careers

Open Positions:

Synthetic and Molecular Biology Scientist / Sr. Scientist

POSITION SUMMARY:

 

Actym Therapeutics is a cutting-edge biotech focused on the discovery and development of novel immuno-oncology therapies, based in Berkeley, California.  We are seeking an experienced Synthetic and Molecular Biology Scientist / Sr. Scientist looking to join a team focused on building a portfolio of therapies based on our STACT platform.  We are a small team, looking to make a huge impact in the field of immunotherapy to treat cancer. The ideal candidate will have multiple accountabilities, including the production of complex immunomodulatory gene payloads, using state of the art techniques in recombinant DNA technology, for tumor-specific delivery using Actym’s therapeutic platform.  In addition, the ideal candidate will assist with in vitro screening studies to identify optimal therapies for clinical development. The candidate should enjoy (and ideally have experience) working in a fast-paced, team-oriented startup environment and possess a strong desire to bring therapeutic benefit to cancer patients.

ESSENTIAL FUNCTIONS AND RESPONSIBILITIES:

These may include, but are not limited to:  

   

  • Significant experience with state-of-the-art techniques in manipulation and cloning of DNA such as synthetic DNA assembly, overlapping PCR, Gibson cloning, etc. is required

  • Ability to work in a multiplexed molecular biology environment managing the in-silico design, synthesis, cloning and validation of multiple DNA constructs in parallel

  • Highly organized and capable of maintaining well curated stocks and libraries of DNA, as well as their corresponding DNA maps

  • Significant experience in the design of biomolecules for improved expression from mammalian cells

  • Working knowledge of bacterial transformation and precision genome engineering methods

  • Expertise in evaluation of cell-based gene expression using qRT PCR, Western Blot, ELISA, Flow cytometry, microscopy is a plus

  • Biotechnology industry experience in a drug discovery environment is a plus

  • Knowledge of BioRad Prime PCR is a plus

  • Comfortable working with dedicated molecular biology software such as SnapGene

  • Experience using MS Office (Word, Power Point, Excel) and graphing software such as Prism 

  • The candidate must be able to work on multiple concurrent projects in a team setting, keep a detailed notebook, and share findings in team meetings in a clear and concise manner

 

EDUCATION:

Ph.D. Molecular Biology or related field + 3-5 years industry experience

 

Actym offers comprehensive and generous health care coverage including: Medical, Dental, Vision. 

 

We look forward to your application.